Dear Professional Colleagues and students wishing u happy Christmas and New Year.

                                     Dr.Devi Shetty, Narayana Hrudayalaya
                                          (Heart Specialist) Bangalore

A chat with Dr.Devi Shetty, Narayana Hrudayalaya

The transcript of the chat is given below. Useful for everyone.


Qn: What are the thumb rules for a layman to take care of his heart?

Ans:
1. Diet - Less of carbohydrate, more of protein, less oil
2. Exercise - Half an hour's walk, at least five days a week; avoid lifts and avoid sitting for a longtime
3. Quit smoking
4. Control weight
5. Control blood pressure and sugar

Qn: Is eating non-veg food (fish) good for the heart?

Ans: No

Qn: It's still a grave shock to hear that some apparently healthy person
gets a cardiac arrest. How do we understand it in perspective?

Ans: This is called silent attack; that is why we recommend everyone past the age of 30 to undergo routine health checkups.

Qn: Are heart diseases hereditary?

Ans: Yes

Qn: What are the ways in which the heart is stressed? What practices do you suggest to de-stress?

Ans: Change your attitude towards life. Do not look for perfection in everything in life.

Qn: Is walking better than jogging or is more intensive exercise required to keep a healthy heart?

Ans: Walking is better than jogging since jogging leads to early fatigue and injury to joints

Qn: You have done so much for the poor and needy. What has inspired you to do so?

Ans: Mother Theresa , who was my patient

Qn: Can people with low blood pressure suffer heart diseases?

Ans: Extremely rare

Qn: Does cholesterol accumulates right from an early age
(I'm currently only 22) or do you have to worry about it only after you are above 30 years of age?

Ans: Cholesterol accumulates from childhood.

Qn: How do irregular eating habits affect the heart ?

Ans: You tend to eat junk food when the habits are irregular and your body's enzyme release for digestion gets confused.

Qn: How can I control cholesterol content without using medicines?

Ans: Control diet, walk and eat walnut.

Qn: Can yoga prevent heart ailments?

Ans: Yoga helps.

Qn: Which is the best and worst food for the heart?

Ans: Fruits and vegetables are the best and the worst is oil.

Qn: Which oil is better - groundnut, sunflower, olive?

Ans: All oils are bad.

Qn: What is the routine checkup one should go through? Is there any specific test?

Ans: Routine blood test to ensure sugar, cholesterol is ok. Check BP, Treadmill test after an echo.

Qn: What are the first aid steps to be taken on a heart attack?

Ans: Help the person into a sleeping position, place an aspirin tablet under the tongue with a sorbitrate tablet if available, and rush him to a coronary care unit since the maximum casualty takes place within the first hour.

Qn: How do you differentiate between pain caused by a heart attack and that caused due to gastric trouble?

Ans: Extremely difficult without ECG.

Qn: What is the main cause of a steep increase in heart problems amongst youngsters? I see people of about 30-40 yrs of age having heart attacks and serious heart problems.

Ans: Increased awareness has increased incidents. Also, s edentary lifestyles, smoking, junk food, lack of exercise in a country where people are genetically three times more vulnerable for heart attacks than Europeans and Americans.

Qn: Is it possible for a person to have BP outside the normal range of 120/80 and yet be perfectly healthy?

Ans: Yes.

Qn: Marriages within close relatives can lead to heart problems for the child. Is it true?

Ans: Yes, co-sanguinity leads to congenital abnormalities and you may not have a software engineer as a child

Qn: Many of us have an irregular daily routine and many a times we have to stay late nights in office. Does this affect our heart? What precautions would you recommend?

Ans: When you are young, nature protects you against all these irregularities. However, as you grow older, respect the biological clock.

Qn: Will taking anti-hypertensive drugs cause some other complications (short / long term)?

Ans: Yes, most drugs have some side effects. However, modern anti-hypertensive drugs are extremely safe.

Qn: Will consuming more coffee/tea lead to heart attacks?

Ans: No.

Qn: Are asthma patients more prone to heart disease?

Ans: No.

Qn: How would you define junk food?

Ans: Fried food like Kentucky, McDonalds, samosas, and even masala dosas.

Qn: You mentioned that Indians are three times more vulnerable. What is the reason for this, as Europeans and Americans also eat a lot of junk food?

Ans: Every race is vulnerable to some disease and unfortunately, Indians are vulnerable for the most expensive disease.

Qn: Does consuming bananas help reduce hypertension?

Ans: No.

Qn: Can a person help himself during a heart attack (Because we see a lot of forwarded emails on this)?

Ans: Yes. Lie down comfortably and put an aspirin tablet of any description under the tongue and ask someone to take you to the nearest coronary care unit without any delay and do not wait for the ambulance since most of the time, the ambulance does not turn up.

Qn: Do, in any way, low white blood cells and low hemoglobin count lead to heart problems?

Ans: No. But it is ideal to have normal hemoglobin level to increase your exercise capacity.

Qn: Sometimes, due to the hectic schedule we are not able to exercise. So, does walking while doing daily chores at home or climbing the stairs in the house, work as a substitute for exercise?

Ans: Certainly. Avoid sitting continuously for more than half an hour and even the act of getting out of the chair and going to another chair and sitting helps a lot.

Qn: Is there a relation between heart problems and blood sugar?

Ans: Yes. Strong relationships since diabetics are more vulnerable to heart attacks than non-diabetics.

Qn: What are the things one needs to take care of after a heart operation?

Ans: Diet, exercise, drugs on time, Control cholesterol, BP, weight.

Qn: Are people working on night shifts more vulnerable to heart disease when compared to day shift workers?

Ans: No.

Qn: What are the modern anti-hypertensive drugs?

Ans: There are hundreds of drugs and your doctor will chose the right combination for your problem, but my suggestion is to avoid the drugs and go for natural ways of controlling blood pressure by walk, diet to
reduce weight and changing attitudes towards lifestyles.

Qn: Does dispirin or similar headache pills increase the risk of heart attacks?

Ans: No.

Qn: Why is the rate of heart attacks more in men than in women?

Ans: Nature protects women till the age of 45. (Present Global census show that the Percentage of heart disease in women has increased than in men )

 Qn: How can one keep the heart in a good condition?

Ans : Eat a healthy diet, avoid junk food, exercise every day, do not smoke and, go for health checkup s if you are past the age of 30 ( once in six months recommended) ....

                                                                                               Samaresh Datta

                                                                                               Asst. Professor

                                                                                               Dept. of Pharmaceutical Chemistry 

                                                                                               A.N.D. College of Pharmacy

                                                                                               Babhnan Gonda, UP

                                                                                               (Mo.+919532552534,+919616613920)

Do You Know?

RECENT MARKETED DRUGS FOR BREAST CANCER

LAPATINIB have been recently launched by GSK PHARMA to stop the production of her2 proteins. And other drug molecule is HERCEPTIN marketed by GENENTECH PHARMA in the USA by the joint collaboration with Roche International. HERCEPTIN is first artificial antibody approved for breast cancer.

TREATMENT OF CANCER

1) RADIATION

It is a process of using UV light as an ionizing radiation to destroy the cancerous cells which infected our body parts of a particular region. The main aim of the radiation therapy is stop the mutation of genes which occur in the DNA replication   under abnormal conditions. It is given in a particular dose form recommended by oncologists. It is mainly seen in Thyroid cancer and in lung cancer.

2) CHEMOTHERAPHY

It is a process of using chemical agents to destroy the cancerous cells. It is mainly applied when the cancer fails to respond to radiation and when the cancer cannot be removed surgically, these groups of chemical agents collectively known as antineoplastic agents. ANTINEOPLASTIC AGENTS acts as an epiphany in the field of tumour chemotherapy. The various categories of drugs have been able to achieve a degree of success while diagnosis the different types of carcinomas and lymphomas. Antineoplastic agents block the biosynthesis of nucleic acids to check the cell division through direct interference with the mitotic spindles. A treatment regimen must be followed while administering these drugs. These drugs are targeting specific so it has got severe side effects which includes G.I complications and Bone marrow depression. These drugs are been discovered on empirical basis since there is qualitative and quantitative differences between human cells and cancerous cells.

MONOCLONAL ANTIBODIES

The production and use of antibodies has become a areas of interest for the research field as well as for the academic purposes for its diversified applications. antibodies are often isolated by conventional method of sacrificing animals after hyperimmunizing them with ANTIGENS. ANTIBODY preparation by this method is usually heterogeneous because the cells are kept on producing a variety of antibodies. Since these antibodies are identical molecules specific for one type of antigen are called MABs (monoclonal antibodies). MABs are now been employed in human disease that are caused by a sudden attack of immune system on the tissue of the body. The most widely used MABs are OKT-3 which has been licensed for clinical use. MABs have been design to form carriers of cytotoxic substances which are termed as immunotoxins. Using MABs it has been possible to separate and remove tumour cells from normal cells of bone marrow. In case of gastrointestinal cancer it is used alone since the antibodies have the tendency to attract the cells of immune system to act against the prevailing cancerous cells. The availability of MABs that recognize immune cell antigens has resulted in improved diagnosis of particular type of lymphomas and leukemia’s.

GENETIC ENGINEERING

It is a process by which the genetic material is manipulated to have a desired result in a predetermine way. It is also known as DNA recombinant technology. The main aim of genetic engineering is to add, remove or repair the part of the genetic material by changing the qualities of a recipient organism in a useful predictable and in a permanent means. It also involves the actual planned synthesis of total new genes designed in advance to possess exactly the right combination of desired properties.

(RECENT ADVANCED TECHNIQUES IN THE TREATMENT OF CANCER)
STEM CELL THERAPY

The stem cell therapy has played the role of epiphany in the field of oncology. With the help of stem cell therapy a hope to live further gets brighter in the case of cancer patients. Stem cell is an undifferentiated cell that is able to renew itself and produce all the specialized cells with an organ. Stem cells occur in much tissue and organ. Scientist has been able to modify the stem cell taken from a bone marrow of a patient and then by the help of genetic engineering the scientist is able to incorporate the stem cell with the drugs which release the therapeutic proteins to kill the brain tumour.

DIFFERENT TYPES OF CANCER

1)    CARCINOMAS- When malignant growth occurs in epithelial tissue covering the body organs- examples: lung cancer and stomach cancer

2)    SARCOMA- These are malignant growth developing in such tissue which are derived from mesoderm- bone cancer

3)    LEUKEMIA-It developed from abnormal proliferation of WBC present in blood and their precursor in the bone marrow. WBC count increases which suppress the production of RBC and platelets- example: Myeloblastic leukaemia.

CONCLUSION-
Human wants are countless. If one want is fulfilled then he will crave for others. IN This process he is able to perceive the bad impacts associated with this cycle, so human beings are falling as a prey to this type of reticent and lethal disease. So the time has come for all of us to wake up against the disease.

BEFORE IT BECOMES TOO LATE FOR US TO REACT, IT IS BETTER TO KILL THE BABY WHEN IT IS IN MOTHER WOMB BEFORE IT SPREAD ITS TENTACLES TO KILL US.

Collected by

Raj Kishore

Asst. Professor

A.N.D.College of Pharmacy

Babhnan, Gonda

                  अम्माँ की गोदी में

मैं न जाने कहाँ कहाँ भटका इस दुनिया की बोगी में,

जब आँख खुली तो खुद पाया अम्माँ की गोदी में.

मुझे  नया संसार मिला था,

एक अनोखा प्यार मिला था,

मानव तन मुझको प्रकृति से उपहार मिला था.

मेरे आने की खबर सुनकर नानी  मौसी आयीं थी,

मेरी खतिर वो खूब खिलोने लायीं थी.

मुझको उठा के मेरी मौसी फिर गांठ लगाई चोटी में,

जब आँख खुली तो खुद को पाया अम्माँ की गोदी में.

एक दिन मेरी हट पर चंदा धरती पर आया था,

मैंने ही तो हांथी को भुरके में बंद कराया था.

जब जब मैं अपनी इन नटखट यादों में खो जाता हूँ ,

बैठ के घर के कोने में अंखियों से अश्रु बहाता हूँ.

हर गलती मेरी माँफ हुई, मैं जब जब पकड़ा जाता चोरी में,

जब आँख खली तो खुद को पाया अम्माँ की गोदी में.

जब  पहली बार मैं जीता था,

जीत नही वो मेरी थी,वो अम्मा मेरी जीती थी,

एक दिन जीत के आऊंगा एसा अम्माँ मेरी कहती थी.

ऐसी मेरी लाखों जीते अम्मा को मेरी अर्पित हैं,

ऐसे मेरे सौ सौ जीवन अम्माँ को मेरी समर्पित हैं.

अम्माँ की मेरी इच्छा थी मैं बिलकुल अशोक महान

बनू,

एक विनय है मेरे मालिक हर जन्म मैं अपनी अम्माँ  का लाल बनू.

याद मुझे अब भी वो दिन है जब पहली बार अम्माँ ने गांठ लगाई थी मेरी लंगोटी में,

जब आँख खुली तो खुद को पाया अम्माँ की गोदी में.

                       सौरभ जयसवाल

                             बी फार्म थर्ड इयर

Teacher's Day Celebrations

Teachers have always been the guiding force for the students, who have inspired them to move ahead and achieve much in life. Teacher's Day is the right time for the students to express their feelings of thankfulness and gratitude towards the teachers. It is a time when students show their affection to them. They play a crucial part in wishing the teachers and expressing all your heartfelt feelings.

All across the world, Teacher's Day celebrations are undertaken to honor teachers for their sincere efforts to impart knowledge to their students. By having celebrations on Teacher's Day, we convey the message that we care for our teachers, just as they do. Celebrating the festival is the recognition of the devotion, with which, teachers undertake the responsibility of educating a child academically as well as morally. On this day, college students dress up like their teachers and teach their juniors, the same way as their teachers do. Sometimes, the teachers also sit in the classes acting like students, reliving the time, when they themselves were students. This creates an understanding between the teachers and their students. Apart from being the day when we give recognition to our teacher's hard work, the festival brings out a healthy interaction between students and teachers, wherein the latter recognizes the teaching capability of the former. Even if it is simple celebrations, they reflect the fact that we care for our teachers.